pentobarbital will reduce the level or outcome of hydrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital will lessen the level or effect of midostaurin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Sturdy CYP3A4 inducers may possibly minimize midostaurin